Addison’s Disease: A Rare but Life-Threatening Endocrine Emergency
Addison’s disease, or Primary Adrenal Insufficiency , is a rare but potentially fatal endocrine disorder. Despite being treatable, it often goes undiagnosed due to its vague and gradual onset. Without timely recognition and appropriate management, it can escalate into a life-threatening Addisonian crisis , characterized by severe hypotension, electrolyte imbalance, hypoglycemia, and circulatory collapse. Why Early Recognition Matters Addison’s disease is frequently misdiagnosed as more common conditions such as chronic fatigue syndrome , depression , or gastrointestinal disorders . This can delay diagnosis and increase the risk of a crisis. Symptoms to Watch For Chronic fatigue and muscle weakness Weight loss and poor appetite Gastrointestinal issues: nausea, vomiting, abdominal pain, diarrhea Dizziness or fainting due to orthostatic hypotension Salt cravings Hyperpigmentation (especially on the palms, gums, areolas, scars, and pressure points) Mood changes or confusi...