Histamine Intolerance: Symptoms, Dietary Triggers, Medications, Diagnosis, and Management
Introduction Since the COVID-19 pandemic, an increasing number of individuals have reported symptoms consistent with histamine intolerance, both alongside Long COVID (LC) and independently. Despite growing interest in a possible connection between COVID-19, ME/CFS, mast cell activation, and histamine-related symptoms, histamine intolerance remains frequently overlooked and dismissed in clinical assessments. Greater awareness and further research are needed to clarify its potential role in persistent post-COVID symptoms and improve diagnostic evaluation and patient care. Histamine intolerance has attracted growing attention, particularly among people experiencing persistent symptoms following COVID-19 infection, including Long COVID and conditions such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Some individuals report recurring digestive problems, skin reactions, headaches, palpitations, fatigue, and other symptoms that appear to worsen after consum...