What is TP53 variant. NCBI's SNP database

By SWA

Some general information about TP53 and its variants.

Example:

TP53 is a gene that plays a critical role in regulating the cell cycle and thus functions as a tumor suppressor. It is involved in preventing cancer formation. Variants (mutations) in the TP53 gene can lead to a loss of this tumor suppressor activity, potentially contributing to the development of cancer.

Specific variants such as – rs730882016, rs730882015, and rs786202315 – are reference SNP IDs used to identify particular mutations in the TP53 gene. These mutations can be single nucleotide polymorphisms (SNPs), insertions, deletions, or other types of genetic variations.

To obtain detailed information about these specific SNPs, such as their location on the gene, their allele information, and their potential clinical significance, you would typically consult databases like NCBI's SNP database or use tools like BioPython to programmatically retrieve this information.

For the most accurate and up-to-date information on these SNPs, I recommend consulting the NCBI SNP database or a similar resource directly. ​

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