Possible Culprits: APS, mRNA, or PEG?

By SWA

As I've noted in various online forums, very little attention has been given to APS (Antiphospholipid Syndrome) and PEG (Polyethylene Glycol). Given my personal medical history—including a confirmed genetic predisposition for von Willebrand Factor (vWF) abnormalities (Types II and V) and a prior thrombosis diagnosis in my left arm—I was understandably alarmed. In 2016, after a bout of sepsis, I received IV vancomycin through a PICC line, along with oral Cipro, which further heightened my concern about potential clotting risks.

In January 2021, I had an elevated D-Dimer, and being familiar with the symptoms of thrombosis, I proactively requested a DVT sonogram. The results confirmed deep vein thrombosis (DVT) in my left lower leg, for which I was prescribed Heparin injections.

Similar symptoms recurred after receiving the mRNA BioNTech COVID-19 vaccine in early 2021—first following the initial dose in March, and again after a booster in May. After several delays in securing appointments, Hematology finally confirmed a diagnosis of APS and lupus in November 2022.

Another incident occurred following a tetanus booster. After accidentally cutting my hand with a kitchen knife, I realized my 10-year tetanus vaccination was overdue. Approximately eight hours after receiving the tetanus shot, I began experiencing familiar symptoms: burning skin, vision and hearing impairment, brain inflammation, and severe muscle weakness. My body seemed to enter a shock-like state, akin to sepsis. Unfortunately, the prescribed treatment—mainly NSAIDs—was inadequate, as NSAIDs can worsen symptoms in people with lupus. Steroids, which might have been more appropriate, were not suggested.

There’s also the question of PEG. White thrombi recently removed from living and deceased patients have unclear consistency, which raises concerns. Given that PEG is a common ingredient in many vaccines and medications, I believe it warrants further investigation as a potential trigger or contributing factor in these reactions.

Case of COVID mRNA Vaccine linked Antiphospholipid Syndrome
https://www.researchsquare.com/article/rs-1574234/v1

Antiphospholipid antibodies and risk of post-COVID-19 vaccination thrombophilia: The straw that breaks the camel's back?
https://pubmed.ncbi.nlm.nih.gov/34090785/

 

 © 2000-2025 Sieglinde W. Alexander. All writings by Sieglinde W. Alexander have a fife year copy right.
Library of Congress Card Number: LCN 00-192742
ISBN: 0-9703195-0-9

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