Selenium and Sodium: Their Divergent Roles in Thyroid and Kidney Disorders
Selenium and sodium are essential micronutrients that play critical yet distinct roles in human physiology. While selenium is particularly significant in thyroid function and autoimmune thyroid disorders, sodium is vital for maintaining fluid balance and regulating blood pressure—functions that are especially important in renal health. This article explores the roles of these two elements in greater scientific depth, highlighting their implications for thyroid and kidney disorders, and discussing recent research findings that extend our understanding of their physiological importance. Selenium and Thyroid Function Selenium is a trace element crucial for the synthesis and activation of thyroid hormones. It is incorporated into selenoproteins, such as iodothyronine deiodinases , which convert the inactive prohormone thyroxine (T4) into the active triiodothyronine (T3). These enzymes are essential for the local and systemic regulation of thyroid hormone activity. Selenium and Hypothyr...