Accelerating discovery: A novel flow cytometric method for detecting fibrin(ogen) amyloid microclots using long COVID as a model

 

Highlights

  • Imaging flow cytometry utilizing a novel rapid flow cytometric detection method is a promising method for detecting amyloid fibrin(ogen) microclots in conditions associated with clotting pathology.
  • While this investigation represents a preliminary study, it lays the foundation for further research into the method's utility as a diagnostic tool for individuals with Long COVID.
  • Though challenging, future research can explore potential correlations between microclot detection and specific Long COVID symptoms and comorbidities, enhancing our understanding of the pathophysiology and tools to detect this condition.
  • The method's ability to evaluate amyloid microclot presence, concentration, and size offers valuable insights for clinical applications.
     
    https://www.cell.com/heliyon/fulltext/S2405-8440(23)06813-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844023068135%3Fshowall%3Dtrue
     

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