Q and A: about health and research

  Monocytes are a type of white blood cell, also known as leukocytes, that play a crucial role in the immune system's defense against infections and other diseases. They are part of the body's innate immune system, which provides immediate, non-specific protection against a wide range of pathogens like bacteria, viruses, and fungi. Here are some key points to understand about monocytes: Origin : Monocytes are produced in the bone marrow from hematopoietic stem cells. These stem cells differentiate into various types of blood cells, including monocytes. Circulation : Once formed, monocytes are released into the bloodstream, where they circulate throughout the body. Phagocytosis : Monocytes are primarily known for their phagocytic activity, which means they can engulf and ingest foreign particles such as bacteria, viruses, and cellular debris. This process helps remove these potentially harmful substances from the body.   Immune Response : Monocytes are part of the first line of...

Von Willebrand factor (VWF), fibrin, and fibrinogen are essential components of the blood clotting process, each with distinct functions: Fibrinogen Production: Fibrinogen is produced primarily in the liver, specifically by hepatocytes (liver cells). It is synthesized and released into the bloodstream. The production of fibrinogen is regulated by various factors, including cytokines and hormones, such as interleukin-6 (IL-6) and interleukin-1 (IL-1). These factors can stimulate the liver to produce more fibrinogen in response to inflammation or injury. Fibrinogen is considered a soluble plasma protein, meaning it circulates in the blood in an inactive form.  Von Willebrand Factor (VWF): VWF facilitates platelet adhesion and aggregation. It acts as a bridge between platelets and damaged blood vessel walls. VWF is produced by endothelial cells and megakaryocytes and plays a role in stabilizing factor VIII. Fibrinogen: Fibrinogen is a soluble plasma protein produced in the liver. It i...

Amyloidosis is a rare and complex group of diseases characterized by the abnormal accumulation of amyloid protein in various organs and tissues of the body. Amyloid is an insoluble, fibrous protein that can build up in different parts of the body, disrupting normal tissue structure and function. There are several types of amyloidosis, each associated with different proteins and organ systems affected. Here are some key points about amyloidosis: Types of Amyloidosis: There are several types of amyloidosis, but the most common ones include: AL Amyloidosis (Immunoglobulin Light Chain Amyloidosis): This type is associated with the accumulation of abnormal immunoglobulin light chain proteins, often produced by abnormal plasma cells in the bone marrow. It can affect various organs, including the heart, kidneys, nervous system, and digestive tract. AA Amyloidosis (Amyloid A Protein Amyloidosis): This type is linked to the buildup of amyloid A protein, which is usually a response to chroni...

Recreant publication regarding elevated hydrogel or PEG was detected in the Covid-19 vaccine that led me to researging the potential harmful consequences.  First findings: The introduction of too much hydrogel into the bloodstream can have several potential consequences, depending on the type of hydrogel, its properties, and the amount introduced. Here are some possible consequences: Hemodilution : Large amounts of hydrogel in the bloodstream can dilute the blood, which may affect the balance of electrolytes, blood cells, and proteins in the blood. Hemodilution can reduce the blood's ability to carry oxygen and nutrients efficiently, potentially leading to symptoms of anemia and impaired circulation. Clotting and Thrombosis : Some hydrogel materials can trigger the activation of the clotting cascade, leading to the formation of blood clots. These clots can block blood vessels, which may result in serious conditions such as deep vein thrombosis (DVT), pulmonary embolism, or stroke. ...

An elevated number of erythrocytes (red blood cells or RBCs) and hemoglobin in the blood can indicate a condition known as polycythemia , or more specifically, polyglobulia . While this can be a temporary and benign finding, it may also be a sign of a more serious underlying health issue — particularly a bone marrow disorder such as Polycythemia Vera (PV) . In this article, we explore what elevated RBC and hemoglobin levels mean, what can cause them, and how PV fits into the picture. What Is an Elevated RBC Count? Red blood cells (erythrocytes) play a crucial role in transporting oxygen from the lungs to the body’s tissues. Hemoglobin , the iron-containing protein in RBCs, is responsible for binding to and carrying oxygen. Normal RBC Count In a healthy person, the RBC count typically falls within a specific range, usually measured in millions of cells per microliter (million/µL) of blood. These ranges vary slightly based on age, sex, and laboratory standards. An RBC count is co...

  The purpose for this explanation is the latest findings of contaminated Pfizer vaccine vials. https://www.spectator.com.au/2023/09/scientists-shocked-and-alarmed-at-whats-in-the-mrna-shots/ The SV40 promoter refers to a specific genetic regulatory element found in the genome of Simian Virus 40 (SV40), a virus that infects monkeys. This promoter region plays a crucial role in the control of gene expression, particularly in the context of molecular biology and genetic engineering. Here's a breakdown of what the SV40 promoter is and how it functions: Promoter: In molecular biology, a promoter is a DNA sequence located at the beginning of a gene. It serves as a binding site for RNA polymerase, an enzyme responsible for initiating transcription, which is the process by which DNA is converted into RNA. Promoters are essential for regulating gene expression because they determine when and to what extent a particular gene is transcribed and, ultimately, translated into a protein. SV40: ...

A theory not researched yet. What virus or bacteria can attack or disable the cell nucleus? Viruses and bacteria typically do not attack or disable the cell nucleus itself. The cell nucleus is a highly protected and essential organelle in eukaryotic cells that contains the cell's genetic material (DNA) and controls many cellular processes. It is surrounded by a double membrane called the nuclear envelope, which acts as a barrier to protect the DNA from external threats. Viruses are much smaller than bacteria and consist of genetic material (either DNA or RNA) surrounded by a protein coat. They lack the cellular machinery necessary to directly attack or disable the cell nucleus. Instead, viruses typically infect cells by binding to specific receptors on the cell's surface and then injecting their genetic material into the cell. Once inside, the viral genetic material can hijack the cell's machinery to replicate itself and produce new virus particles, ultimately leading to t...

Tetrahydrobiopterin (BH4) is a critical cofactor in the synthesis of neurotransmitters in the brain, including serotonin, dopamine, and norepinephrine. It plays a vital role in regulating mood, emotion, and various cognitive functions. A deficiency in BH4 can lead to various neurological and psychiatric disorders, including a condition called phenylketonuria (PKU). PKU is a genetic disorder that impairs the body's ability to break down the amino acid phenylalanine, leading to a buildup of this amino acid in the bloodstream. This can result in brain damage and intellectual disabilities if not managed properly. While PKU primarily affects cognitive and neurological function, it can also have emotional and behavioral implications. Overview of Tetrahydrobiopterin Deficiency and Hyperphenylalaninemia Introduction to Tetrahydrobiopterin (BH4) Deficiency and Hyperphenylalaninemia Tetrahydrobiopterin (BH4) Deficiency (GS224) is a metabolic disorder that affects the body's ability to s...

Definition of autoimmune disease and some examples of specific conditions: Rheumatoid Arthritis (RA): Rheumatoid arthritis is an autoimmune disorder that primarily affects the joints. It leads to chronic inflammation, pain, and swelling in the joints, and if left untreated, it can cause joint deformities and damage. RA typically affects multiple joints symmetrically and can also affect other organs in the body. Lupus (Systemic Lupus Erythematosus or SLE): Lupus is a chronic autoimmune disease that can affect various parts of the body, including the skin, joints, kidneys, heart, and nervous system. It often presents with a wide range of symptoms, including skin rashes, joint pain, and fatigue. The severity of lupus varies among individuals. Multiple Sclerosis (MS): Multiple sclerosis is an autoimmune disease that primarily affects the central nervous system, including the brain and spinal cord. It leads to the destruction of the protective covering of nerve fibers (myel...

Once my endocrinologist, who diagnosed me with diabetic II told me a trick. "Never start with cereal or any other carb". I have learned to start my morning with protein, meaning an egg, a little slice of cheese, etc.. It worked for me ever since.  Then there is Thiamine ( B1) Thiamine plays a crucial role in the metabolism of carbohydrates, and carbohydrates, in turn, affect thiamine absorption and utilization. Here's how they interact: Thiamine in Carbohydrate Metabolism: Thiamine is a coenzyme that is essential for several enzymatic reactions involved in the metabolism of carbohydrates. It plays a key role in converting glucose (a simple carbohydrate) into energy in the form of adenosine triphosphate (ATP) through a process called glycolysis. Without adequate thiamine, the metabolism of carbohydrates is impaired, and energy production is compromised. Carbohydrates and Thiamine Absorption: The absorption of thiamine in the gastrointestinal tract can be influenced b...

For years I have been following a tradition, drinking a big cup of hot tea with bread and cold cuts for a light dinner. Not good, as I had to find out. "There is a link between this and needing a colonoscopy." Tea has tannins, oxalates, & phytates, which bind iron, decreasing absorption, causing iron deficiency anemia, causing doctors to order colonoscopies to look for bleeds. Tea tannins, oxalates, and phytates are compounds found in tea and other plant-based foods and beverages.  They can have both positive and negative effects on health, depending on the context and consumption levels. Here's an overview of each of these compounds: Tannins: What are they? Tannins are a class of polyphenolic compounds found in various plants, including tea leaves. They are responsible for the astringency or bitterness of tea. Health Effects: Tannins have both antioxidant and anti-inflammatory properties, which can be beneficial for health. They may help protect against certain chr...

  B12 (vitamin B12) and methylfolate (a form of vitamin B9) are two important vitamins that play crucial roles in various physiological processes within the body. They are both essential for overall health, particularly in relation to the metabolism and nervous system. Here's an overview of each: Vitamin B12 (Cobalamin): Function: Vitamin B12 is necessary for several bodily functions, including the formation of red blood cells, DNA synthesis, neurological function, and the metabolism of fatty acids and amino acids. Sources: Natural sources of vitamin B12 are mainly animal products such as meat, fish, eggs, and dairy. It's not typically found in plant-based foods, making it challenging for vegetarians and vegans to obtain adequate B12 without supplementation. Absorption: The absorption of vitamin B12 requires a protein called intrinsic factor, which is produced by the stomach. Some medical conditions, such as pernicious anemia, can affect intrinsic factor production, leading ...

Amino acids are organic compounds that serve as the building blocks of proteins in living organisms. There are 20 standard amino acids that are commonly found in proteins, each with its own unique structure and function. These amino acids can be categorized into several groups based on their properties and functions. Here, I'll explain the general functions of amino acids, keeping in mind that each individual amino acid contributes to protein structure and function in its own specific way: Structural Function : Glycine : Glycine is the simplest amino acid and is often found in collagen, the primary structural protein in the body.   Glycine in food: Meat and Poultry : Glycine is present in relatively high amounts in meat and poultry products. Pork and chicken, in particular, are good sources. Fish : Certain types of fish, such as cod and salmon, contain glycine. Gelatin : Gelatin is derived from the collagen found in animal connective tissues and is a rich source of glycine. It is c...

The most overlooked, or denied origin of illnesses.  Unless there is scientific evidence that dispute this publication, I´m convinced Michael D. De Bellis , MD, MPH and Abigail Zisk A.B. has delivered plausible evidence that many people suffer a damaged immune response, by experience of early trauma: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968319/ Search this paper for: "The Immune System and Childhood Trauma" "Activation of the immune system involves the production of cytokines, which promote an inflammatory reaction to infection or pathogens in the body. Although one of the main effects of this reaction is to produce the physical symptoms of sickness (e.g., fever, nausea, and fatigue), activation of cytokines that promote inflammation are implicated in depression, a common outcome of early trauma." Further information : Childhood trauma can indeed have a significant impact on both mental and physical health, and there is growing evidence to suggest t...

Diverse environmental fungi are increasingly recognized as causal or contributory factors in a wide range of chronic inflammatory conditions. These include common cutaneous disorders such as atopic dermatitis (eczema) and onychomycosis, as well as mucosal inflammatory diseases such as pharyngitis, laryngitis, esophagitis, asthma, chronic rhinosinusitis, vaginosis, and colitis¹. In immunocompromised individuals, cutaneous candidal infections, manifesting as mucocutaneous candidiasis, often take on a more invasive and destructive course¹,². Beyond these well-characterized associations, emerging evidence also implicates fungi in systemic and neuroinflammatory diseases, including rheumatoid arthritis³ and Alzheimer’s disease (AD), highlighting their broader role in human pathology. Rheumatoid arthritis (RA), a chronic autoimmune disease primarily affecting the joints, is commonly associated with the development of firm, non-tender subcutaneous nodules near pressure points or joints. These...