Muscle Weakness - Myositis is a Autoimmune Condition

What is myositis?

Myositis is the name for a group of rare conditions that can cause muscles to become weak, tired and painful. The word myositis simply means inflammation in muscles. If something is inflamed, it may be swollen. Myositis can affect people of any age, including children.

Myositis is an inflammation of the muscles, typically caused by an autoimmune response where the body's immune system mistakenly attacks its own muscle tissue. This leads to symptoms such as muscle weakness, pain, and swelling. 

In addition: 
Conclusions and Relevance This cohort study found that individuals who received any COVID-19 vaccine were more likely to be diagnosed with inflammatory musculoskeletal disorders than those who did not. This information will be useful in clarifying the adverse reactions to COVID-19 vaccines and informing people about their potential for inflammatory musculoskeletal disorders after vaccination.
https://www.medrxiv.org/content/10.1101/2023.11.14.23298544v1

What are the three stages of myositis?

Myositisossificans is a benign, self-limiting process, characterized by three distinct stages:early, intermediate, and mature.

What is the cause of myositis?

Most types of myositis are autoimmune conditions, where the body's immune system attacks itself, causing swelling of the muscles and joints.

Does myositis go away?

There's no cure for myositis, but in most cases, treatment can put it into remission. Most people with myositis have it for the rest of their lives. People with myositis have an increased risk of developing rhabdomyolysis.

What does myositis pain feel like?

This inflammation usually results in muscle fatigue and weakness, frequent falling, swelling of the feet and legs, and muscular and joint pain. Early symptoms in patients with myositis include: Difficulty standing up from a seated position. Difficulty climbing stairs.

What are the first signs of myositis?

Symptoms

    Difficulty standing up from a seated position.

    Difficulty climbing stairs.

    Difficulty lifting the arms.

    Fatigue after standing or walking a long time.

    Trouble swallowing or breathing.

    Muscle pain that does not subside within a few weeks.

    A red or purple colored rash on the eyelids, elbows, knees and knuckles.

Is myositis a serious illness?

Occasionally, myositis can affect breathing and swallowing. This may occur at the start of severe cases when the muscles used for these important tasks become weak. On rare occasions, this condition may cause weakening of the heart.

Where does myositis start?

The main muscles to be affected are around the shoulders, hips and thighs. Having myositis can also lead to other parts of the body being affected, such as the skin, lungs or heart. Sometimes myositis can affect the muscles that carry out tasks such as breathing and swallowing.

Is myositis caused by stress?

For those of us with chronic autoimmune diseases, such as the idiopathic inflammatory myopathies, generally referred to as myositis, stress can be even more damaging. It has been shown that stress can diminish our immune system, cause disease, and increase inflammation.

Can you fully recover from myositis?

Like other rheumatic diseases, myositis is unlikely to go away on its own. But with proper treatment and management these chronic diseases can be brought under control. At present there is no cure for myositis. A person with myositis will need to manage the condition and to adjust to the changes it brings.

What foods should you avoid if you have myositis?

Reduce the number of foods made with wheat flour and sugar, especially bread, pasta, and most packaged snack foods. Choose instead foods containing whole grains, such as brown rice and bulgur wheat. Decrease intake of saturated fat by eating less animal fats and products made with palm kernel oil.

What happens if myositis is left untreated?

Myositis: Muscle Inflammation | Inflammatory Myopathy | HSS

If left untreated, the muscle inflammation in myositis can lead to permanent muscle damage and loss of muscle mass. Myositis can be associated with problems in other organs like the joints and the lungs. In dermatomyositis, there is usually a rash or skin inflammation in addition to the muscle inflammation.

What is the best treatment for myositis?

Drugs. The first choice of treatment of myositis is steroids, which are usually given in high doses to begin with. Steroids can be given as tablets or injections. They should reduce the inflammation quickly, settle muscle pain and the feeling of being unwell.

What is another name for myositis?

More often, however, the term myositis is used to refer to a disease involving chronic inflammation of the muscles, often occurring together with other symptoms. This condition is also known as idiopathic inflammatory myopathy (IIM).

Where does myositis hurt?

Myositis can affect people of any age, including children. The main muscles to be affected are around the shoulders, hips and thighs. Having myositis can also lead to other parts of the body being affected, such as the skin, lungs or heart.

Can Covid bring on myositis?

SARS-CoV-2 mediates infection using the ACE-2 receptor as a host, suggesting that covid-19 can directly infect skeletal muscle causing the inflammatory response seen in myopathies such as covid-19-induced myositis. Thus, muscle weakness and myalgia are commonly reported symptoms of covid-19.

Does myositis affect the brain?

Myositis can be an invisible illness, meaning you may look perfectly healthy on the outside but are terribly ill nonetheless. Myositis can cause “brain fog” making concentration, organization, and other related tasks difficult. Myositis causes a variety of symptoms and affects each person differently.

What age is myositis most common?

Sporadic inclusion body myositis (sIBM): The most common form, it tends to impact those older than 50 and more often in men than women. It progresses more slowly than other forms and manifests in the smaller muscles of the hands and forearms, impacting a person's grip and fine motor skills.

How rare is myositis?

Polymyositis and dermatomyositis affect only 6-8 people out of 100,000. They mostly affect adults, but children can be affected by a type of dermatomyositis (juvenile dermatomyositis). Inclusion body myositis is the most common acquired muscle disease in people over 50, but it is still a rare disease.

What fruits are good for myositis?

Vegetables: carrots, broccoli, squash. Fruits: bananas, oranges and apples. Dairy: milk, yogurt and cheese.

What vitamins help myositis?

Consume enough calcium and vitamin D through food and/or supplements. Dairy products are excellent sources of calcium. Consume low-fat milk, cheese and yogurt regularly. If you are lactose intolerant, choose Lactaid milk or calcium fortified soy milk.

What tests confirm myositis?

Myositis Diagnosis & Treatment | Mount Sinai - New York

The diagnosis of myositis involves a complete physical exam, blood test, electromyography (a neurological test that assess the electrical activity in your muscles), and a muscle biopsy, which involves removing a small sample of muscle tissue for testing.

Can myositis spread?

Myositis due to bacterial infection often results from contiguous spread from adjacent sites of infection, penetrating injury, ischemia, foreign body, and hematogenous spread. Staphylococcus aureus often spreads through the hematogenous route.

Myositis is inflammation especially of the voluntary muscles, characterized by localized or diffuse pain, tenderness on movement or palpation, swelling, and/or weakness. The two main categories of myositis include non‐infectious and infectious. Infective myositis may be due to a wide variety of pathogens, including bacteria, fungi, viruses, and parasites. A brief account of the various pathogens causing infective myositis is discussed.

Myositis Causes, Symptoms, and Treatments:
https://www.upmc.com/services/rheumatology/conditions/myositis