Q and A: about health and research

Case Presentation A young adult presented to the emergency department with progressive sensory disturbances and weakness in both arms and legs. There were no signs of bladder dysfunction, infection, prior significant medical conditions, or a vegetarian diet. The patient reported recreational nitrous oxide (N₂O) use over the past six months, with approximately 150 applications, several times per week. Clinical and Diagnostic Findings Neurological examination revealed a transverse spinal cord syndrome, with symptoms more pronounced in the lower extremities and a defined sensory level at thoracic segment T8. Magnetic resonance imaging (MRI) of the cervical spine (T2-weighted) demonstrated a long segment of intramedullary hyperintensity from vertebral body C2 to C5. Axial images showed a characteristic inverted “V” pattern in the posterior columns—typical for subacute combined degeneration (SCD) or funicular myelopathy. There was no radiological or clinical evidence of peripheral nerve ...

Celiac disease, also known as gluten-sensitive enteropathy, is an autoimmune condition where the body’s immune system reacts abnormally to gluten—a protein found in wheat, rye, and barley. This response results in damage to the small intestine and impaired nutrient absorption. Another closely related condition, Dermatitis Herpetiformis (DH) , is a skin manifestation of celiac disease, presenting as intensely itchy, blistering rashes. Both conditions share a common underlying cause: intolerance to gluten, specifically to the gliadin fraction of gluten, which triggers an autoimmune response. In this article, we'll explore the details of celiac disease and dermatitis herpetiformis, their symptoms, diagnosis, and treatment, as well as key dietary considerations for those affected. In addition: ATI (Amylase/Trypsin Inhibitors) are proteins found in wheat and other cereals. They're part of the plant's natural defense system against pests, but in humans, they can trigger immune r...