The Unresolved Biology of ME/CFS: Viruses, Bacteria, and Mitochondrial Damage
In my previouspost , I examined two unresolved historical questions: first, how long it took the scientific community to confirm Dr. Carleton Gajdusek’s discovery of Kuru; and second, whether Gajdusek’s work would ever have been validated had Stanley Prusiner’s scrapie research not led to the development of the “protein-only” prion hypothesis. This raises an important parallel question: are we now facing a similar situation with ME/CFS? My central concern is whether ME/CFS is primarily associated with a viral or bacterial origin. To date, scientific research has focused predominantly on viral explanations, while bacterial mechanisms have received comparatively limited attention as potential contributors or vectors. Another important issue is whether bacteria can reside within mitochondria, leading to mitochondrial rupture and eventual cell death. Current evidence suggests that this is indeed possible. Many pathogenic bacteria are known to exploit mitochondrial functions in ways...