Melkersson-Rosenthal Syndrome (MRS) and diarrhea in Crohn’s disease
Melkersson-Rosenthal Syndrome (MRS) Melkersson-Rosenthal Syndrome (MRS) is a rare neurological disorder characterized by a triad of symptoms: Recurrent facial paralysis (facial nerve palsy) : This involves weakness or paralysis on one side of the face that comes and goes. Swelling (edema) of the face and lips (orofacial edema) : Particularly the upper lip, though other areas of the face can also be involved. Fissured tongue (lingua plicata or scrotal tongue) : The tongue appears grooved or cracked, often without causing pain. The exact cause of MRS is unknown, but it's believed to be related to immune or inflammatory processes, and possibly genetic factors. Some cases of MRS have been linked with conditions like Crohn's disease and sarcoidosis, which are also inflammatory in nature. While the full triad of symptoms is classic, many patients may only have one or two of these signs, making diagnosis difficult. Treatment often involves corticosteroids or other anti-inflammatory ...